Stephnie Weir (born November 28, 1967; sometimes credited as Stephanie Weir) is an American actress and comedian. Weir is most notable for her membership in the recurring cast of comedians on sketch comedy series MADtv.
Stephnie Weir was born in Odessa, Texas. She attended Odessa College where she majored in theater and broadcasting. Weir then transferred to Southern Illinois University at Edwardsville, where she majored in anthropology and women's studies. After moving to Chicago, Weir began performing at the Improv Olympic and later on The Second City's main stage and the Goodman Theatre. Weir teamed up with her husband, Robert Dassie, to form the comedy duo WeirDass.
Weir joined the cast of MADtv in 2000 as a feature performer, for the sixth season. However, Weir was later promoted to a repertory performer status the following season. Weir left MADtv in January 2006, midway through her sixth season of the show. Weir had announced in 2005 (season ten) that she would be leaving. However, fellow cast members Aries Spears and Paul Vogt would leave as well, and Ron Pederson would be let go by FOX due to budget cuts, so in order for the viewers to feel a sense of continuation, Weir was persuaded to stay on the show until half way through season 11. Some of her famous characters included naive, lisping high school student Angela Wright, drama queen Dorothy Lanier, hyperactive kid Dot Goddard, party girl doctor Kylie Johnson, cat-loving Lillian Verner Game Show champion Gail Cinder, Leona Campbell (based on Weir's real-life grandma), Kappa Kappa Kappa sorority sister Mackenzie Shaw, and stroke-prone Muriel Westig. She also gained notoriety for her offbeat impersonations of Anna Nicole Smith and Laura Bush.