Although Reeves was born in New York, she was raised in the countryside of New Hampshire by her academic parents, who preferred not to own a television but rather submerge their children in the vast realms of literature. Thus, her educational background ranged from years abroad in France and Italy to the Ivy League colleges of the United States. Drama studies were what really interested her, however, resulting in her choosing an acting career.

She currently stars on the HBO comedy series Entourage as "Mrs. Ari". Other notable roles include "Marissa" opposite Will Ferrell in the film Old School and "Jessie" in the film Mr. and Mrs. Smith. She has also had parts in the political comedy American Dreamz and the horror film Child's Play 3.