Natacha Régnier was attracted to theatre from her early adolescence. Her first screen role was in The Motorcycle Girl (1993), a short film by Stéphan Carpiaux. After that, she played a number of roles for French television.
The confirmation of her talent came in 1998, when Régnier and Élodie Bouchez received the Prix d'interprétation féminine at the Cannes Film Festival for their role in La vie rêvée des anges by Eric Zonca.
She has stated that her hero is Sandrine Bonnaire.
Natacha has dated Jeremie Renier and was married to the musician Yann Tiersen however they are currently filing for divorce. They have a daughter who is 4 years old.
Regnier has just finished the film Une journée, which is now in post-production.
