Kelley landed his first major animation role when he was cast as the lead in Steven Spielberg's Invasion America for The WB Network. The show became the first dramatic animated series to air in primetime on network television.
As a veteran voice over actor, Mikey has lent his talent to several animated projects including King of the Hill, Scooby-Doo and the Cyber Chase, All Grown Up, Ben 10, Loonatics Unleashed, Rocket Power, and The Land Before Time, among several others. Kelley has also been featured in a variety of video games including Tony Hawk's Underground, Full Spectrum Warrior, Viewtiful Joe, Ratchet and Clank, Metal Gear Solid: Portable Ops, and Halo 3.
On the commercial front, he is currently working on a host of television and radio campaigns including those for Mercedes-Benz, McDonalds, Verizon Wireless, Mattel, and is the voice of Toon Disney.
Kelley was also the voice of Michelangelo in the Teenage Mutant Ninja Turtles movie.