Condon was born in Goodland, Indiana. After some time playing ukulele, he switched to banjo and was a professional musician by 1921. He was based in Chicago for most of the 1920s, and played with such jazz notables as Bix Beiderbecke and Frank Teschemacher.
In 1928 Condon moved to New York City. He frequently arranged jazz sessions for various record labels, sometimes playing with the artists he brought to the recording studios, including Louis Armstrong and Fats Waller. He organised racially-integrated recording sessions - when these were still rare - with Waller, Armstrong and Henry 'Red' Allen. He played with the band of Red Nichols for a time. Later, from 1938 he had a long association with Milt Gabler's Commodore Records.
From the late 1930s on he was a regular at the Manhattan jazz club Nick's. The sophisticated variation on Dixieland music which Condon and his colleagues created there came to be nicknamed "Nicksieland." By this time, his regular circle of musical associates included Wild Bill Davison, Bobby Hackett, Edmond Hall and Pee Wee Russell.
Condon also did a series of jazz radio broadcasts from New York's Town Hall during 1944-45 which were nationally popular. These recordings survive, and have been issued on the Jazzology label.
From 1945 through 1967 he ran his own New York jazz club, Eddie Condon's. In the 1950s Condon recorded a sequence of classic albums for Columbia Records. The musicians involved in these albums - and at Condon's club - included Wild Bill Davison (cornet), Billy Butterfield (trumpet), Edmond Hall, Peanuts Hucko, Pee Wee Russell, Cutty Cutshall, Lou McGarity (trombone), Bud Freeman, Gene Schroeder, Dick Carey, Ralph Sutton (piano), Bob Casey, Walter Page, Jack Lesberg, Al Hall (bass), George Wettling (drums), Buzzy Drootin (drums), Cliff Leeman (drums).
Condon toured Britain in 1957 with a band including Wild Bill Davison, Cutty Cutshall, Gene Schroeder and George Wettling. His last tour was in 1964, when he took a band to Australia and Japan. Condon's men, on that tour, were a roll-call of top mainstream jazz musicians: Buck Clayton (trumpet), Pee Wee Russell (clarinet), Vic Dickenson (trombone), Bud Freeman (tenor sax), Dick Carey (piano and alto horn), Jack Lesberg (bass), Cliff Leeman (drums), Jimmy Rushing (vocals). A nice touch was that Billy Banks, a vocalist who had recorded with Condon and Pee Wee Russell in 1932, and had lived in obscurity in Japan for many years, turned up at one of the 1964 concerts: Pee Wee asked him "have you got any more gigs?".
In 1948 his autobiography We Called It Music was published. The book has many interesting and entertaining anecdotes about musicians Condon worked with. Eddie Condon's Treasury of Jazz (1956) was a collection of articles by various writers co-edited by Condon and Richard Gehman.
A latter-day collaborator, clarinetist Kenny Davern, described a Condon gig: "It was always a thrill to get a call from Eddie and with a gig involved even more so. I remember eating beforehand with Bernie (Previn; trumpet) and Lou (McGarity; trombone) and everyone being in good spirits. There was a buzz on, we'd all had a taste and there was a great feel to the music" (from the notes to 'Kenny Davern: A Night With Eddie Condon', Arbors Records CDARCD 19238).
Eddie Condon toured and appeared at jazz festivals through 1971. He died in New York City.
References to Condon are common in the BBC Radio 4 parody series Down the Line.
