Anton attended R.M. Marrs junior high school, graduated from Omaha Burke High School and attended University of Nebraska at Kearney. He began his career as a college circuit comedian in the 1980s. In 1984 he traveled the Mediterranean and Middle East as part of an all-comedy USO tour where he spent two months in Turkey, Greece, Bahrain, Italy, Israel and Spain entertaining troops. In 1985 he was named Showtime's Funniest Person in Nebraska.
In the late 1980s, Anton moved to New York City. He now lives in Los Angeles, California with his wife Lesley Barr their two daughters. Anton's mother lives in Las Vegas, Nevada and his father lives in Houston, Texas with his new wife, Eileen McBay Anton.
As of March 2006, Anton is currently living in Los Angeles, California with his wife, two children, their Australian shepherd, Wayne and cat, Snow White. He guest starred on ABC's drama series Boston Legal as Ray Richardson in the episode "Word Salad Days" on March 28 ,2006. Anton made a guest appearance in HBO's comedy series Entourage on July 23, 2006 in the episode "Strange Days". As of July 2006, Anton is currently shooting the movie Careless which opens in theaters 2007.
During his three year tenure, Anton received limited screen time on the show. He primarily did a stand-up segment during some episodes. Aside from his stand-up routine, Anton was often cast as an extra or supporting character. Anton's most enduring character was Clorox from the "Star Trek: Deep Stain Nine" sketches. Clorox was supposed to be the main nemesis of the sketch and he was loosely based on Q from the Star Trek series. Anton also impersonated Dennis Miller and Nate Richert. Anton left MADtv in 1998, at the end of the third season.
Since leaving MADtv, Anton developed an extensive resume on television. He co-starred in several television series, including shows like The Army Show (1998), Random Play (1999) and Primetime Glick (2001). In the late 1990s, Anton guest star television series credits included Mr. Show with Bob and David (1995); Expert Truck Singer and Coach (1996). During the 2000s, Anton appeared in shows like Curb Your Enthusiasm (2000); The King of Queens (2001, 2005); Ally McBeal (2001); Lizzie McGuire (2001); Everybody Loves Raymond (2002) and Weekends at the D.L. (2005). Anton has also appeared on shows like Premium Blend (1997) and Late Friday (2001) where he performed his stand-up routine.
In Phil of the Future Anton plays Lloyd Diffy, a father and a paranoid engineer trying to fix a broken time machine. Lloyd's main goal is to find a way so that he and his family can return to their home in the year 2121 from the year 2004, in which they find themselves stranded. In addition, Lloyd is a lover of older music and he works at a hardware store. He is also very paranoid about the government figuring out he and his family are from the future.
Anton has also promoted the show in other mediums. He had also appeared on the Disney Channel's Express Yourself segments alongside other members of the Phil of the Future cast.
Anton has appeared in many films. His film credits include Mail Bonding (1995), Deliver Us From Eva (2003), The Goldfish (2003) and Run Ronnie Run (2002). His most recent film was the 2005, D-WAR, in which he played an American hostage. His upcoming movie Careless opens in 2007.
In 2004, Anton currently stars in the animated series Tom Goes to the Mayor. He provides the voice (and body) of one of the three city council member.
Along with comedians Ron Lynch and Brendon Small, Craig hosts the Tomorrow Show, a weekly live comedy show at the Steve Allen Theatre in Los Angeles, California.
Anton was nominated for the National Association for Campus Activities Campus Entertainer of the Year award three times.
